Join our mailing list!
(Your shopping cart is empty)
Diane Publishing Books
Genetically Modified Model Report on Toxicology and Carcinogenesis Study of Phenolphthalein (CAS No. 77-09-8) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Feed Study)
J.K. Dunnick (ed); D.E. Malarkey (ed) M.A. Hanes (ed)
Phenolphthalein (PH) was commonly used as a laxative for most of the 20th cent. The use of PH in laxatives has decreased since 1997 when the FDA proposed to withdraw its classification as an OTC drug. PH has been previously evaluated in carcinogenecity studies in 1996. The major route of human exposure to PH is via ingestion, dermal contact, & inhalation of contaminated air originating from process units manufacturing the compound. In this study, the carcinogenic effects of PH were studied in the haploinsufficient p16Ink4a/p19Arf mouse model as an ongoing goal to seek model systems for toxicology & carcinogenesis studies, especially those that can provide mechanistic info. relative to understanding an agentís model of action. Illustrations.
Travelerís Self Care Manual: A Self Help Guide to Emergency Medical Treatment for the Traveler
Sagas of Icelanders: A Selection
In the Combat Zone: Special Forces Since 1945
Fourth Book of Sexual Questions & Answers
Rudy!: An Investigative Biography of Rudy Giuliani
Share your knowledge of this product with other customers...
Be the first to write a review
Diane Publishing Co
PO Box 617
Darby, PA 19023-0617
Become an Affiliate
Send Us Feedback
Copyright ï¿½ 2004 Diane Publishing Company. All Rights Reserved.