Anthrax: Agency Approaches to Validation and Statistical Analyses Could Be Improved

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By Timothy M. Persons (au)
Year: 2014
Pages: 77
Binding Paperback
ISBN 978-1-4578-6567-1

Product Code: 145786567X

Description

In 2001, the FBI investigated an intentional release of B. anthracis, a bacterium that causes anthrax, which was identified as the Ames strain. Subsequently, FBI contractors developed and validated several genetic tests to analyze B. anthracis samples for the presence of certain genetic mutations. The FBI had previously collected and maintained these samples in a repository. This report addresses (1) the extent to which these genetic tests were scientifically verified and validated; (2) the characteristics of an adequate statistical approach for analyzing samples, whether the approach used was adequate, and how it could be improved for future efforts; and (3) whether any remaining scientific concerns regarding the validation of genetic tests and statistical approaches need to be addressed for future analyses. Tables and figures. This is a print on demand report.

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