Toxicology & Carcinogenesis Studies of 2-Methylimidazole (CAS NO. 693-98-1) in F344/N Rats & B6C3F1 Mice (Feed Studies)

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Our Price: $45.00

Year: 2004
Pages: 292
Binding Paperback

Product Code: 0756746868

Description

P.C. Chan (ed). 2-Methylimidazole is used in the manufacture of pharmaceuticals, photographic chemicals, dyes & pigments, ag. chemicals, & rubber. It has been identified as a byproduct in foods & has been detected in mainstream & sidestream tobacco. smoke. 2-Methylimidazole was nominated by the Nat. Cancer Institute for a long-term study because of the high potential for human exposure & a lack of carcinogenicity studies in rodents. Male & female F2344/N rats & B6C3F1 mice were exposed to 2-methylimidazole (99.5% pure) in feed for 2 years. Chapters: Explanation of levels of evidence of carcinogenic activity; Tech. Reports Review Subcomm. & Summary of their comments; Intro.; Materials & Methods; Results; Discussion & Conclusions. Illus.

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