Toxicology & Carcinogenesis Studies of Stoddard Solvent IIC (CAS NO. 64742-88-7) in F344/N Rats & B6C3F1 Mice (Inhalation Studies)

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Year: 2004
Pages: 274
Binding Paperback

Product Code: 0756745918

Description

R.S. Chabra (ed). White spirit (also called mineral spirit) is a complex mixture of solvents derived from oil. The most widely used white spirit in the paint industry is called Stoddard solvent (SS), & it is also used as a dry cleaning agent & as a solvent for cleaning & degreasing. The Nat. Toxicology Program studied SS IIC to determine if it caused cancer in rats or mice. There were more deaths in male & female rats exposed to the highest concentration of SS than in other animal groups. There were no differences in survival of mice exposed to the solvent. Male rats exposed to SS IIC had higher rates of tumors of the adrenal gland, & female mice exposed to SS IIC had slightly increased rates of liver adenomas. Tables & graphs.

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