Join our mailing list!
(Your shopping cart is empty)
Diane Publishing Books
Toxicology and Carcinogenesis Studies of Transplacental 3’-Azido-3’-deoxythymidine (AZT) (CAS No. 30516-87-1) in Swiss (CD-1) Mice (“In Utero” Studies)
W.G. Lieuallen (ed)
3’-Azido-3’-deoxythymidine (AZT) is the most widely used agent for the treatment of people with AIDS or seropositive for HIV. AZT was known to cause cancer in mice born to mothers exposed to doses of 400 mg per kg of body weight or higher during pregnancy. This study exposed female mice to lower concentrations of AZT (50-300 mg AZT/kg body weight) before & during pregnancy to determine if those doses also caused cancer in the offspring. The study concludes that exposure of pregnant female mice to AZT resulted in increased rates of lung cancer in their male offspring. There was no difference in cancer in female offspring of mothers exposed to 300 mg AZT/kg body weight or less during pregnancy. Charts & tables.
Japanese Experience: A Short History of Japan
Karluk: The Great Untold Story of Arctic Exploration
We the People: Voices & Images of the New Nation
Mammoth Book of Cats: A Collection of Stories, Verse & Prose
Dynamic Nutrition for Maximum Performance: A Complete Nutritional Guide for Peak Sports Performance
Share your knowledge of this product with other customers...
Be the first to write a review
Diane Publishing Co
PO Box 617
Darby, PA 19023-0617
Become an Affiliate
Send Us Feedback
Copyright ï¿½ 2004 Diane Publishing Company. All Rights Reserved.