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Toxicology and Carcinogenesis Studies of Sodium Chlorate (CAS No. 7775-09-9) in F344/N Rats and B6C3F1 Mice (Drinking Water Studies)
M.J. Hooth (ed)
Sodium chlorate is used as an oxidizing agent & bleach for paper pulp; to make chlorine dioxide used in water disinfection; in ore processing; in the manufacture of matches & explosives; in dye making & the printing & dyeing of fabrics; in leather finishing & tanning; to make perchlorates; in toothpaste & mouthwash; & as a non-selective herbicide, defoliant, & harvest aid. Chlorate is found as a stable byproduct in drinking water that has been disinfected with chlorine dioxide. Sodium chlorate is being studied because of widespread consumer exposure to treated drinking water & lack of carcinogenicity data. Genetic toxicology studies were conducted in Salmonella typhimurium & mouse peripheral blood erythrocytes. Tables & illustrations.
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