Join our mailing list!
(Your shopping cart is empty)
Diane Publishing Books
Genetically Modified Model Report on Toxicology and Carcinogenesis Study of Glycidol (CAS No. 556-52-5) in Genetically Modified Haploinsufficient p16Ink4a/p19Arf Mice (Gavage Study)
J.K. Dunnick (ed)
Glycidol is used as a chemical intermediate in the pharmaceutical industry, as a stabilizer in the manufacture of vinyl polymers, and as an intermediate in the synthesis of glycerol, Glycidol ethers, and amines. Glycidol was nominated for carcinogenecity study by the Environmental Protection Agency (EPA). Glycidol was selected for study in the haploinsufficient p16Ink4a/p19Arf mouse because it was found to be carcinogenic in rats and mice in conventional 2-year rodent studies (NTP, 1990), but was negative in a study in p53+/- mice (Tennant et al., 1999). In this study, male and female mice received Glycidol (greater than 95% pure) by gavage for 40 weeks. Genetic toxicology studies were conducted in mouse peripheral blood erythrocytes. Illustrations.
Applique: The Ann Boyce Way
Secret World of the Spy: Stories of Espionage, Deception & Discovery
Not Fade Away: The On-Line World Remembers Jerry Garcia
Commonwealth of Science: ANZAAS & the Scientific Enterprise in Australia, 1888-1988
Share your knowledge of this product with other customers...
Be the first to write a review
Diane Publishing Co
PO Box 617
Darby, PA 19023-0617
Become an Affiliate
Send Us Feedback
Copyright ï¿½ 2004 Diane Publishing Company. All Rights Reserved.