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Diane Publishing Books
Interim Within-Season Estimate of the Effectiveness of Trivalent Inactivated Influenza Vaccine -- Marshfield, Wisconsin, 2007-08 Influenza Season
Frederic E. Shaw (ed)
During clinical trials, the efficacy of vaccination with inactivated influenza vaccines for the prevention of influenza infection has been estimated as high as 70%-90% among healthier adults. However, the effectiveness of annual influenza vaccination typically is lower during those influenza seasons when a sub-optimal match between the vaccine strains and circulating influenza strains is observed. Findings demonstrate that, in any season, assessment of the clinical effectiveness of influenza vaccines cannot be determined solely by laboratory evaluation of the degree of antigenic match between vaccine and circulation strains. Patients living in an area surrounding Marshfield, WI participated in this study, which is described in detail. Tables.
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