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Diane Publishing Books
Neurobiology of Cocaine Addiction: A Reprint from “Science and Practice Perspectives”
Eric J. Nestler (au)
Cocaine produces its psychoactive & addictive effects primarily by acting on the brain’s limbic system, a set of interconnected regions that regulate pleasure & motivation. An initial, short-term effect -- a buildup of the neurochemical dopamine -- gives rise to euphoria & a desire to take the drug again. Researchers are seeking to understand how cocaine’s many longer term effects produce addiction’s persistent cravings & risk of relapse. This paper focuses on the buildup of the genetic transcription factor DeltaFosB in the limbic system which correlate with addiction-like behaviors in mice & may precipitate very long-lasting changes to nerve cell structure. This is one of the first steps toward an understanding of the transition from cocaine abuse to addiction.
It’s Never Too Late to Get Rich: Secrets of Building a Nest Egg at Any Age
Baby Bonding: Giving Your Child a Secure Start to Life
Dried Flower Arranger’s Bible
Reading from the Heart: Women, Literature & the Search for True Love
Around the American Table: Treasured Recipes & Food Traditions from the American Cookery Collections of the New York Public Library
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