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Diane Publishing Books
Neurobiology of Cocaine Addiction: A Reprint from “Science and Practice Perspectives”
Eric J. Nestler (au)
Cocaine produces its psychoactive & addictive effects primarily by acting on the brain’s limbic system, a set of interconnected regions that regulate pleasure & motivation. An initial, short-term effect -- a buildup of the neurochemical dopamine -- gives rise to euphoria & a desire to take the drug again. Researchers are seeking to understand how cocaine’s many longer term effects produce addiction’s persistent cravings & risk of relapse. This paper focuses on the buildup of the genetic transcription factor DeltaFosB in the limbic system which correlate with addiction-like behaviors in mice & may precipitate very long-lasting changes to nerve cell structure. This is one of the first steps toward an understanding of the transition from cocaine abuse to addiction.
Between Friends: Writing Women Celebrate Friendship
McGraw-Hill Multimedia Handbook
Anti-Depressant Survival Program: How to Beat the Side Effects & Enhance the Benefits of Your Medication
Commonwealth of Science: ANZAAS & the Scientific Enterprise in Australia, 1888-1988
Fourth Book of Sexual Questions & Answers
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